Diethyl phosphorothionochloridate
Diethyl chlorothiophosphate
CAS: 2524-04-1
Molecular Formula: C4H10ClO2PS
Diethyl phosphorothionochloridate - Names and Identifiers
Diethyl phosphorothionochloridate - Physico-chemical Properties
| Molecular Formula | C4H10ClO2PS |
| Molar Mass | 188.61 |
| Density | 1.2g/mLat 25°C(lit.) |
| Melting Point | -75℃ |
| Boling Point | 96 °C |
| Flash Point | >230°F |
| Water Solubility | hydrolyzes, immiscible |
| Vapor Presure | 1.4 mm Hg ( 50 °C) |
| Appearance | liquid |
| Color | Colorless to Red to Green |
| Refractive Index | n20/D 1.472(lit.) |
| Physical and Chemical Properties | Colorless to light amber transparent liquid. melting point -75 ℃ boiling point 49 ℃ relative density 1.202 refractive index 1.4715 solubility insoluble in water, soluble in organic solvents. |
| Use | For the synthesis of phoxim, parathion, 203, chlorpyrifos, triazophos and diazinon and other organophosphorus pesticides |
Diethyl phosphorothionochloridate - Risk and Safety
| Risk Codes | R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R34 - Causes burns R26 - Very Toxic by inhalation R21/22 - Harmful in contact with skin and if swallowed. |
| Safety Description | S23 - Do not breathe vapour. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S28A - |
| UN IDs | UN 2751 8/PG 2 |
| WGK Germany | 3 |
| RTECS | TD1780000 |
| HS Code | 29309099 |
| Hazard Class | 8 |
| Packing Group | II |
Diethyl phosphorothionochloridate - Upstream Downstream Industry
| Raw Materials | Chlorine Sodium hydroxide Phosphorus pentasulfide Phosphorus pentoxide Phosphorus pentoxide Ethyl Alcohol |
| Downstream Products | parathion Phoxim Triazophos quintiofos Profenofos |
Diethyl phosphorothionochloridate - Nature
Open Data Verified Data
colorless to light amber clear liquid. Boiling point 49 C (133Pa). The relative density was 1.202. Melting Point -75 °c. Refractive index 4715. Insoluble in water, soluble in organic solvents. Alcoholysis in alcohol or sodium alcohol. Stable at room temperature, isomerization slowly at 100 °c.
Last Update：2024-01-02 23:10:35
Diethyl phosphorothionochloridate - Preparation Method
Open Data Verified Data
- O-ethyl thiophosphoric acid dichloride is produced by the reaction of trichlorothiophos with anhydrous ethanol, which is then mixed with an excess of anhydrous ethanol, and alkali powder is added to produce 0, O′-diethyl thiophosphoric acid dichloride.
- phosphorus pentasulfide method the reaction of phosphorus pentasulfide with anhydrous ethanol produces 0,O'-ethyl dithiophosphoric acid, and then reacts with chlorine at low temperature to produce 0,O: diethyl thiophosphoryl chloride.
- in the ethanol alkali powder method, the dichlorides are generated by the reaction of the phosphorus trichlorosulfon with excess anhydrous ethanol; The dichlorides are mixed with the excess anhydrous ethanol, and the alkali powder is added to generate ethyl chloride.
- The sodium ethoxide method is derived from the interaction of sodium ethoxide with phosphorus trichloride.
Last Update：2022-01-01 10:38:16
Diethyl phosphorothionochloridate - Use
Open Data Verified Data
This product is an intermediate of organophosphorus pesticide, which can be used to prepare parathion, phoxim, zhimiling, 1605, 1059 and Suhua 203.
Last Update：2022-01-01 10:38:15
Diethyl phosphorothionochloridate - Safety
Open Data Verified Data
- this product and some raw materials are toxic, irritating to eyes, skin and mucous membranes. Inhalation of vapor can cause tracheitis and pulmonary edema, and absorption through skin can cause poisoning. Its toxicity and control method see 0,0 'dimethyl thiophosphoryl chloride.
- intermediate. Can be used in galvanized drum or plastic drum closed packaging. Store in a cool and ventilated place to prevent heat and fire. According to the provisions of toxic and flammable storage and transportation.
Last Update：2022-01-01 10:38:16
Diethyl phosphorothionochloridate - Reference Information
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| Use | Used to synthesize organophosphorus pesticides such as phoxim, parathion, 203, chlorpyrifos, triazophos and diazinon O,O-diethyl thiophosphoryl chloride is abbreviated as ethyl chloride, is an important pesticide intermediate, used for the synthesis of organophosphorus insecticides parathion, phoxim, diazinon, quinoxathion, pyridazinon, triazophos, pyrimidoxy, borer, chlorpyrifos, endogenous phosphorus and synergist phosphorus, etc., can also be used as lubricating oil additives and other sulfur-containing organic phosphorus compounds synthesis raw materials. |
| Production method | At present, the domestic industrial production of ethyl chloride mainly adopts the phosphorus pentasulfide method, that is, the phosphorus pentasulfide first reacts with ethanol to obtain ethyl sulfide, and then chlorination to obtain ethyl chloride. The by-product sulfur chloride can be decomposed by sodium sulfite. However, this method consumes a large amount of sodium sulfite, has huge production equipment, and produces a large amount of wastewater, making it difficult to treat the three wastes. Therefore, the new process uses sodium sulfide to decompose sulfur chloride, which improves the quality of chloride and the purity can reach more than 97%. S2Cl2 Na2S → 2NaCl 3S ↓ The required sodium sulfide is obtained by absorbing the hydrogen sulfide from the exhaust gas of the previous process through caustic soda. The precipitated sulfur is crystalline and can be used to produce sulfuric acid or phosphorus pentasulfide. The specific process is as follows: the ethyl sulfide prepared by the phosphorus pentasulfide route is pumped into the chlorination reactor, stirred and cooled to 15 ℃, chlorine gas is introduced, the chlorination temperature is controlled at 25~28 ℃ (30~35 ℃ in winter), the chlorine gas passing speed is about 40 ~ 50kg/h, and the chlorine gas pressure is about 0.1kPa. The generated hydrogen chloride gas is neutralized and discharged through lime, and after 1h of reaction, crude ethyl chloride is obtained with a content of 63% ~ 67% and a yield of about 94%. Then add the crude ethyl chloride product to the ethyl chloride product, add the composite co-catalyst, add the 18% sodium sulfide aqueous solution dropwise at 5-25 ℃, and react at 5-30 ℃ for 10-20min after adding, The refined liquid is filtered and layered, and the oil layer is rinsed with clear water to obtain the product with a content of 96%-98% and no free alkali. In addition, the methods for preparing ethyl chloride include trichothion method, sodium ethoxide method, ethanol alkali powder method, etc. |
| category | corroded articles |
| toxicity classification | poisoning |
| acute toxicity | oral-rat LD50:1340 mg/kg; Oral-mouse LD50: 800 mg/kg |
| flammability hazard characteristics | flammability |
| storage and transportation characteristics | warehouse ventilation and low temperature drying; Store separately from alkali and oxidant |
| fire extinguishing agent | sand, dry powder, carbon dioxide |
| occupational standard | STEL 1 mg/m3 |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 02:00:07
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Raw Materials for Diethyl phosphorothionochloridate
Chlorine
Sodium hydroxide
Phosphorus pentasulfide
Phosphorus pentoxide
Phosphorus pentoxide
Ethyl Alcohol
Sodium hydroxide
Phosphorus pentasulfide
Phosphorus pentoxide
Phosphorus pentoxide
Ethyl Alcohol
Downstream Products for Diethyl phosphorothionochloridate